Basic Information
ID: ALA5138417
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-primed human THP-1 cells assessed as suppression of ATP-induced cleaved caspase -1 secretion preincubated for 30 mins followed by MSU stimulation for 4 hrs by western blot analysis
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA5138417
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.30 | 3.05 | 3.05 |