Assay Report Card

Basic Information

ID: ALA5138418

Type: Binding

Description: Inhibition of NLRP3 inflammasome activation in LPS-primed human THP-1 cells assessed as suppression of ATP-induced GSDMD cleavage preincubated for 30 mins followed by MSU stimulation for 4 hrs by western blot analysis

Organism: Homo sapiens

Cell type: THP-1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
266.303.053.05