Basic Information
ID: ALA5138419
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774A.1 cells assessed as reduction in nigericin induced IL-1beta secretion at 100 uM preincubated for 30 mins followed by ATP stimulation and measured after 30 mins by western blot analysis
Format: BAO_0000219
Organism: Mus musculus
Cell type: J774.A1
Target: NACHT, LRR and PYD domains-containing protein 3(ALA3779755)
Document: ALA5137000
Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774A.1 cells assessed as reduction in nigericin induced IL-1beta secretion at 100 uM preincubated for 30 mins followed by ATP stimulation and measured after 30 mins by western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5138419
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.30 | 3.05 | 3.05 |