Assay Report Card

Basic Information

ID: ALA5138420

Type: Binding

Description: Inhibition of NLRP3 inflammasome activation in LPS-primed C57BL/6 mouse BMDMs assessed as suppression of nigericin induced GSDMD cleavage at 100 uM preincubated for 30 mins followed by nigericin stimulation and measured after 30 mins by western blot analysis

Organism: Mus musculus

Strain: C57BL/6

Cell type: BMDM

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
266.303.053.05