Basic Information
ID: ALA5138422
Type: Binding
Description: Inhibition of NLRP3 inflammasome activation in LPS-primed C57BL/6 mouse BMDMs assessed as suppression of nigericin induced IL-1beta release preincubated for 30 mins followed by nigericin stimulation and measured after 30 mins by ELISA
Format: BAO_0000219
Organism: Mus musculus
Strain: C57BL/6
Cell type: BMDM
Target: NACHT, LRR and PYD domains-containing protein 3(ALA3779755)
Document: ALA5137000
Inhibition of NLRP3 inflammasome activation in LPS-primed C57BL/6 mouse BMDMs assessed as suppression of nigericin induced IL-1beta release preincubated for 30 mins followed by nigericin stimulation and measured after 30 mins by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5138422
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 266.30 | 3.05 | 3.05 |