Assay Report Card

Basic Information

ID: ALA5138423

Type: Binding

Description: Inhibition of NLRP3 inflammasome activation in LPS-primed mouse J774.A1 assessed as suppression of nigericin induced IL-1beta release preincubated for 30 mins followed by nigericin stimulation and measured after 30 mins by ELISA

Organism: Mus musculus

Cell type: J774.A1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
266.303.053.05