Assay Report Card

Basic Information

ID: ALA5138424

Type: Binding

Description: Inhibition of AIM2 inflammasome activation in LPS-primed human THP-1 cells assessed as increase in JNK phosphorylation at 10 uM preincubated for 30 mins followed by overnight stimulation with poly(dA:dT) by western blot analysis

Organism: Homo sapiens

Cell type: THP-1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
266.303.053.05