Basic Information
ID: ALA5138538
Type: Binding
Description: Inhibition of human recombinant full-length DNMT1 expressed in Sf9 cells assessed as inhibition of methylated dI-dC formation using poly dI-dC and [Me-3H]SAM as substrate incubated for 2 hrs by liquid scintillation counting analysis
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA5138538
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.42 | -1.44 | -1.44 |
| 478.64 | 5.18 | 5.18 |
| 536.57 | -2.22 | -2.22 |
| 550.60 | -1.83 | -1.83 |
| 374.42 | -1.50 | -1.50 |
| 620.62 | -3.85 | -3.85 |
| 402.47 | -0.72 | -0.72 |
| 652.69 | -3.30 | -3.30 |
| 505.49 | -3.40 | -3.40 |
| 385.42 | -1.86 | -1.86 |
| 665.71 | -3.22 | -3.22 |
| 550.60 | -1.48 | -1.48 |
| 522.54 | -2.26 | -2.26 |
| 634.65 | -3.20 | -3.20 |
| 606.60 | -3.89 | -3.89 |
| 634.65 | -3.46 | -3.46 |
| 533.55 | -2.97 | -2.97 |
| 357.37 | -2.64 | -2.64 |