Basic Information
ID: ALA5138540
Type: Binding
Description: Inhibition of human C-terminal domain DNMT1 catalytic domain (351 to 1600 residues) expressed in Escherichia coli BL21-CodonPlus (DE3)-RIL cells assessed as inhibition of methylated dI-dC formation using 5 ug/ml poly dI-dC and [Me-3H]SAM as substrate incubated for 2 hrs by liquid scintillation counting analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5138540
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 634.65 | -3.20 | -3.20 |