Basic Information
ID: ALA5138943
Type: Binding
Description: Inhibition of recombinant human PRMT1 assessed as residual activity using biotinylated histone H4 (1 to 21) as substrate incubated for 60 mins in presence of SAM by AlphaLISA method
Format: BAO_0000357
Organism: Homo sapiens
Target: Protein-arginine N-methyltransferase 1(ALA5524)
Document: ALA5137016
Inhibition of recombinant human PRMT1 assessed as residual activity using biotinylated histone H4 (1 to 21) as substrate incubated for 60 mins in presence of SAM by AlphaLISA method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5138943
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 432.39 | 4.44 | 4.44 |
| 358.40 | 2.23 | 2.23 |
| 387.44 | 1.98 | 1.98 |
| 358.40 | 1.92 | 1.92 |
| 387.44 | 2.11 | 2.11 |
| 386.45 | 2.57 | 2.57 |
| 344.37 | 1.84 | 1.84 |
| 358.40 | 2.10 | 2.10 |
| 368.39 | 2.74 | 2.74 |
| 373.41 | 1.72 | 1.72 |
| 370.41 | 1.90 | 1.90 |
| 373.41 | 0.86 | 0.86 |
| 522.56 | 2.73 | 2.73 |
| 423.43 | 3.10 | 3.10 |
| 384.44 | 1.99 | 1.99 |
| 497.57 | 4.22 | 4.22 |
| 359.39 | 1.33 | 1.33 |
| 372.43 | 2.49 | 2.49 |
| 372.43 | 2.31 | 2.31 |
| 348.42 | 2.35 | 2.35 |
| 373.41 | 1.59 | 1.59 |
| 386.45 | 2.70 | 2.70 |
| 354.37 | 2.65 | 2.65 |
| 359.39 | 1.63 | 1.63 |
| 386.45 | 2.53 | 2.53 |
| 372.43 | 2.44 | 2.44 |
| 372.43 | 2.18 | 2.18 |