Basic Information
ID: ALA5138953
Type: Binding
Description: Selectivity index, ratio of IC50 for inhibition of human full length recombinant FLAG-tagged PRMT5 (2 to 637 residues) using histone H2A as substrate to IC50 for inhibition of human full length recombinant GST-tagged PRMT4 (2 to 608 residues) using histone H3 as substrate
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5138953
Selectivity Index
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 622.64 | 0.39 | 0.39 |
| 648.68 | 0.95 | 0.95 |
| 650.70 | 1.17 | 1.17 |
| 664.72 | 1.56 | 1.56 |
| 650.70 | 1.17 | 1.17 |
| 608.62 | 0.00 | 0.00 |
| 636.67 | 0.78 | 0.78 |
| 636.67 | 0.78 | 0.78 |