Basic Information
ID: ALA5138979
Type: Binding
Description: Inhibition of PI3Kalpha in rat Rat1 cells assessed as reduction in phosphorylation of AKT at Ser473 residue incubated for 1 hr by cellular assay
Organism: Rattus norvegicus
Cell type: Rat1
Activity Charts
Bioactivity
Activity Types for Assay ALA5138979
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 513.65 | 2.15 | 2.15 |
| 469.55 | 5.89 | 5.89 |
| 410.40 | 1.81 | 1.81 |
| 359.39 | -0.52 | -0.52 |
| 411.39 | 1.21 | 1.21 |
| 486.50 | 3.55 | 3.55 |
| 441.41 | 1.11 | 1.11 |
| 458.47 | 1.21 | 1.21 |
| 421.46 | 1.89 | 1.89 |
| 455.40 | 1.08 | 1.08 |
| 556.57 | 1.15 | 1.15 |
| 453.38 | 1.10 | 1.10 |
| 474.49 | 2.99 | 2.99 |
| 425.37 | 1.72 | 1.72 |
| 411.34 | 1.33 | 1.33 |
| 441.37 | 0.69 | 0.69 |
| 441.37 | 0.69 | 0.69 |
| 411.39 | 1.75 | 1.75 |
| 410.36 | 1.93 | 1.93 |
| 455.40 | 1.08 | 1.08 |
| 455.40 | 1.08 | 1.08 |
| 408.38 | 2.10 | 2.10 |
| 455.40 | 1.08 | 1.08 |
| 441.37 | 0.69 | 0.69 |
| 440.43 | 1.17 | 1.17 |
| 485.47 | 3.42 | 3.42 |
| 409.41 | 2.42 | 2.42 |
| 455.40 | 1.08 | 1.08 |
| 469.42 | 1.47 | 1.47 |
| 425.37 | 1.72 | 1.72 |
| 424.38 | 2.32 | 2.32 |
| 441.37 | 0.69 | 0.69 |
| 455.40 | 1.08 | 1.08 |
| 409.37 | 1.51 | 1.51 |
| 411.47 | 0.42 | 0.42 |
| 464.41 | 2.00 | 2.00 |
| 422.41 | 2.49 | 2.49 |