Basic Information
ID: ALA5139763
Type: Binding
Description: Inhibition of N-terminal human TRKA (436 to 790 residues) expressed in baculovirus expression system using TK as substrate measured after 30 mins in presence of ATP by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5139763
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 428.44 | 2.95 | 2.95 |
| 362.41 | 4.41 | 4.41 |
| 471.31 | 5.63 | 5.63 |
| 428.45 | 5.65 | 5.65 |
| 366.38 | 4.30 | 4.30 |
| 409.29 | 4.78 | 4.78 |
| 366.38 | 4.30 | 4.30 |
| 392.41 | 4.86 | 4.86 |
| 434.37 | 5.31 | 5.31 |
| 445.27 | 5.06 | 5.06 |
| 471.31 | 5.63 | 5.63 |
| 384.37 | 4.43 | 4.43 |
| 364.84 | 4.67 | 4.67 |
| 366.38 | 4.30 | 4.30 |
| 374.42 | 4.73 | 4.73 |
| 380.40 | 4.60 | 4.60 |
| 400.82 | 4.95 | 4.95 |
| 344.81 | 2.89 | 2.89 |
| 380.40 | 4.60 | 4.60 |
| 348.39 | 4.16 | 4.16 |
| 384.37 | 4.43 | 4.43 |
| 414.39 | 4.92 | 4.92 |
| 410.46 | 5.51 | 5.51 |
| 380.40 | 4.55 | 4.55 |
| 344.42 | 4.33 | 4.33 |
| 460.41 | 5.88 | 5.88 |
| 426.86 | 5.52 | 5.52 |
| 434.37 | 5.31 | 5.31 |
| 348.39 | 4.16 | 4.16 |
| 398.39 | 5.04 | 5.04 |
| 400.82 | 4.95 | 4.95 |
| 426.86 | 5.52 | 5.52 |
| 355.41 | 3.89 | 3.89 |
| 366.38 | 4.30 | 4.30 |
| 410.40 | 5.00 | 5.00 |
| 366.38 | 4.30 | 4.30 |
| 384.37 | 4.43 | 4.43 |
| 406.44 | 5.17 | 5.17 |
| 406.44 | 5.17 | 5.17 |