Basic Information
ID: ALA5140069
Type: Binding
Description: Inhibition of NLRC4 inflammasome in LPS-primed mouse J774.A1 cells assessed as IL-1beta secretion at 10 uM preincubated for 1 hr followed by flagellin addition and measured after 6 hrs by ELISA relative to control
Organism: Mus musculus
Cell type: J774.A1
Activity Charts
Bioactivity
Activity Types for Assay ALA5140069
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 543.06 | 5.06 | 5.06 |
| 559.15 | 5.26 | 5.26 |
| 503.05 | 3.83 | 3.83 |
| 532.04 | 4.04 | 4.04 |
| 530.11 | 5.41 | 5.41 |
| 559.10 | 5.48 | 5.48 |
| 577.21 | 6.33 | 6.33 |
| 517.12 | 5.35 | 5.35 |
| 508.57 | 3.28 | 3.28 |
| 510.68 | 4.26 | 4.26 |
| 496.61 | 3.20 | 3.20 |
| 595.19 | 6.07 | 6.07 |
| 566.14 | 6.64 | 6.64 |
| 581.16 | 6.14 | 6.14 |
| 442.56 | 3.07 | 3.07 |