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Assay Report Card

Basic Information

ID: ALA5140071

Type: Binding

Description: Inhibition of NLRC4 inflammasome in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr followed by flagellin addition and measured after 6 hrs by ELISA

Organism: Mus musculus

Cell type: J774.A1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
543.065.065.06
559.155.265.26
595.196.076.07