Basic Information
ID: ALA5140072
Type: Binding
Description: Inhibition of AIM2 inflammasome in LPS-primed mouse J774.A1 cells assessed as reduction in IL-1beta secretion preincubated for 1 hr followed by poly(dA:dT) addition and measured after 4 hrs by ELISA
Organism: Mus musculus
Cell type: J774.A1
Activity Charts
Bioactivity
Activity Types for Assay ALA5140072
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 543.06 | 5.06 | 5.06 |
| 559.15 | 5.26 | 5.26 |
| 595.19 | 6.07 | 6.07 |