Basic Information
ID: ALA5140112
Type: Binding
Description: Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) at 100 nM using dihydroorotate as substrate by DCIP based microplate reader analysis relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: Dihydroorotate dehydrogenase(ALA1966)
Document: ALA5137035
Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) at 100 nM using dihydroorotate as substrate by DCIP based microplate reader analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5140112
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.21 | 3.00 | 3.00 |
| 356.33 | 4.48 | 4.48 |
| 368.41 | 4.96 | 4.96 |
| 404.39 | 5.24 | 5.24 |
| 402.85 | 5.62 | 5.62 |
| 402.85 | 5.62 | 5.62 |
| 400.43 | 5.41 | 5.41 |
| 356.35 | 3.80 | 3.80 |
| 396.42 | 4.75 | 4.75 |
| 402.85 | 5.62 | 5.62 |
| 398.43 | 4.97 | 4.97 |
| 412.42 | 4.69 | 4.69 |
| 436.41 | 5.98 | 5.98 |
| 404.39 | 5.24 | 5.24 |
| 386.40 | 5.10 | 5.10 |
| 418.47 | 6.12 | 6.12 |
| 398.43 | 4.83 | 4.83 |
| 382.44 | 5.27 | 5.27 |
| 384.41 | 4.58 | 4.58 |
| 450.44 | 5.51 | 5.51 |
| 387.39 | 4.50 | 4.50 |
| 416.88 | 5.93 | 5.93 |
| 438.50 | 5.75 | 5.75 |
| 387.39 | 4.50 | 4.50 |
| 484.89 | 6.17 | 6.17 |
| 436.41 | 5.98 | 5.98 |
| 412.46 | 5.36 | 5.36 |
| 370.38 | 4.19 | 4.19 |
| 384.41 | 4.58 | 4.58 |
| 386.40 | 5.10 | 5.10 |
| 412.46 | 5.36 | 5.36 |
| 408.43 | 5.71 | 5.71 |
| 416.88 | 5.93 | 5.93 |
| 452.40 | 5.86 | 5.86 |
| 418.47 | 6.12 | 6.12 |
| 382.39 | 4.36 | 4.36 |
| 386.40 | 5.10 | 5.10 |
| 338.36 | 3.66 | 3.66 |
| 398.43 | 4.97 | 4.97 |