Basic Information
ID: ALA5140186
Type: Binding
Description: Inhibition of C-terminal poly-His-tagged human recombinant KLK5 (30 to 293 residues) transfected in CHO cells assessed as inhibition constant using Boc-VPR-AMC as fluorogenic substrate incubated for 30 mins by fluorescence plate reader assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA5140186
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 870.02 | -3.32 | -3.32 |
| 2159.44 | ||
| 2781.11 | ||
| 982.11 | -4.56 | -4.56 |
| 855.01 | -4.31 | -4.31 |
| 1004.16 | ||
| 1119.25 | ||
| 2105.44 | ||
| 957.11 | -2.25 | -2.25 |
| 1119.25 | ||
| 2073.40 | ||
| 1168.33 | ||
| 869.04 | -3.92 | -3.92 |
| 1005.15 | ||
| 2219.61 | ||
| 1319.49 | ||
| 1255.40 | ||
| 2105.44 | ||
| 956.12 | -2.85 | -2.85 |
| 3080.44 | ||
| 981.12 | -5.16 | -5.16 |
| 2257.60 |