Basic Information
ID: ALA5140258
Type: Binding
Description: Inhibition of recombinant GST-tagged wild type ALK (1064 to 1427 residues) (unknown origin) expressed in Sf9 cells using TMB peptide as substrate preincubated for 10 mins followed by ATP addition and measured after 15 mins by ELISA analysis
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA5140258
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.35 | 5.04 | 5.04 |
| 576.67 | 8.41 | 8.41 |
| 460.56 | 5.67 | 5.67 |
| 595.71 | 7.79 | 7.79 |
| 462.57 | 6.44 | 6.44 |
| 494.64 | 7.47 | 7.47 |
| 524.67 | 6.88 | 6.88 |
| 442.57 | 5.53 | 5.53 |
| 515.71 | 6.59 | 6.59 |
| 568.72 | 7.41 | 7.41 |
| 512.63 | 7.61 | 7.61 |
| 512.58 | 7.32 | 7.32 |
| 474.61 | 6.31 | 6.31 |
| 592.67 | 8.40 | 8.40 |
| 458.61 | 6.70 | 6.70 |
| 568.68 | 6.75 | 6.75 |
| 576.67 | 8.41 | 8.41 |
| 508.67 | 7.39 | 7.39 |
| 522.65 | 7.03 | 7.03 |
| 584.72 | 6.90 | 6.90 |
| 474.61 | 6.31 | 6.31 |
| 513.62 | 7.00 | 7.00 |
| 477.01 | 6.19 | 6.19 |
| 516.69 | 5.46 | 5.46 |
| 444.58 | 6.31 | 6.31 |
| 524.83 | ||
| 591.80 | 7.86 | 7.86 |
| 366.47 | 4.12 | 4.12 |
| 554.69 | 7.11 | 7.11 |
| 537.69 | 5.68 | 5.68 |
| 462.57 | 6.44 | 6.44 |
| 582.70 | 7.05 | 7.05 |
| 376.89 | 4.79 | 4.79 |
| 524.67 | 7.38 | 7.38 |
| 472.59 | 5.54 | 5.54 |
| 462.57 | 6.44 | 6.44 |
| 510.64 | 7.59 | 7.59 |
| 512.58 | 7.32 | 7.32 |
| 460.56 | 5.67 | 5.67 |
| 472.64 | 6.98 | 6.98 |
| 544.70 | 8.62 | 8.62 |
| 488.64 | 6.70 | 6.70 |
| 522.81 | ||
| 526.61 | 7.71 | 7.71 |
| 478.56 | 5.79 | 5.79 |
| 573.14 | 8.34 | 8.34 |
| 520.68 | 7.72 | 7.72 |
| 479.03 | 6.96 | 6.96 |
| 568.72 | 7.41 | 7.41 |
| 494.64 | 7.47 | 7.47 |
| 561.69 | 6.25 | 6.25 |
| 568.72 | 7.41 | 7.41 |
| 510.56 | 6.55 | 6.55 |
| 445.57 | 5.70 | 5.70 |
| 478.56 | 5.79 | 5.79 |
| 585.76 | 8.36 | 8.36 |
| 270.34 | 4.89 | 4.89 |
| 472.59 | 5.94 | 5.94 |
| 566.71 | 7.18 | 7.18 |
| 431.54 | 6.23 | 6.23 |
| 567.71 | 6.99 | 6.99 |
| 570.69 | 6.60 | 6.60 |
| 674.85 | 8.99 | 8.99 |
| 375.93 | 4.63 | 4.63 |
| 525.60 | 6.70 | 6.70 |
| 539.71 | 6.06 | 6.06 |
| 532.69 | 7.40 | 7.40 |
| 304.31 | 4.37 | 4.37 |
| 274.32 | 4.39 | 4.39 |
| 376.46 | 6.56 | 6.56 |
| 594.76 | 8.70 | 8.70 |