Basic Information
ID: ALA5140269
Type: Functional
Description: Resistance index, ratio of IC50 for cytotoxicity against mouse BaF3 cells harboring crizotinib resistant NPM/ALK I1171N mutant to IC50 for cytotoxicity against mouse BaF3 cells harboring crizotinib resistant wild type NPM/ALK assessed as inhibition of cell proliferation incubated for 72 hrs by MTS assay
Organism: Mus musculus
Cell type: BaF3
Activity Charts
Bioactivity
Activity Types for Assay ALA5140269
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 508.67 | 7.39 | 7.39 |