ID: ALA5140419
Type: Binding
Description: Inhibition of SARS CoV-2 main protease at 50 uM using DABCYL-KTSAVLQSGFRKM-E(EDANS)-NH2 as substrate preincubated for 30 mins followed by substrate addition and measured after 20 mins relative to control
Format: BAO_0000357
Organism: Severe acute respiratory syndrome coronavirus 2
Target: Replicase polyprotein 1ab(ALA4523582)
Document: ALA5137045
Inhibition of SARS CoV-2 main protease at 50 uM using DABCYL-KTSAVLQSGFRKM-E(EDANS)-NH2 as substrate preincubated for 30 mins followed by substrate addition and measured after 20 mins relative to control: 1
Bioactivity
Activity Types for Assay ALA5140419
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
419.22 | 5.10 | 5.10 |
245.31 | 2.11 | 2.11 |
303.34 | 2.07 | 2.07 |
314.20 | 3.42 | 3.42 |
290.30 | 2.02 | 2.02 |
290.30 | 2.02 | 2.02 |
471.43 | 2.78 | 2.78 |
303.34 | 2.07 | 2.07 |
471.43 | 2.78 | 2.78 |
392.37 | 2.93 | 2.93 |
342.27 | 1.58 | 1.58 |
274.24 | 1.86 | 1.86 |
419.46 | 4.18 | 4.18 |
366.40 | 4.18 | 4.18 |
334.40 | 3.26 | 3.26 |
373.39 | 2.33 | 2.33 |
346.30 | 2.11 | 2.11 |
409.40 | 6.41 | 6.41 |
295.37 | 3.27 | 3.27 |
384.36 | 1.19 | 1.19 |
305.38 | 2.28 | 2.28 |
433.41 | 4.98 | 4.98 |
421.46 | 4.57 | 4.57 |
323.76 | 2.47 | 2.47 |
295.37 | 3.27 | 3.27 |
323.76 | 2.47 | 2.47 |
393.47 | 3.95 | 3.95 |
303.34 | 2.12 | 2.12 |
323.76 | 2.47 | 2.47 |
493.52 | 4.74 | 4.74 |
314.32 | 1.99 | 1.99 |
476.52 | 3.97 | 3.97 |
502.45 | 3.00 | 3.00 |
302.29 | 2.72 | 2.72 |
500.48 | 3.60 | 3.60 |
461.35 | 4.26 | 4.26 |
480.48 | 4.78 | 4.78 |
466.45 | 4.47 | 4.47 |
496.48 | 4.48 | 4.48 |
510.42 | 4.83 | 4.83 |
496.48 | 4.48 | 4.48 |
296.36 | 2.66 | 2.66 |
399.86 | 4.62 | 4.62 |
264.29 | 1.65 | 1.65 |
500.90 | 5.13 | 5.13 |
307.31 | 1.95 | 1.95 |
414.42 | 4.57 | 4.57 |
299.36 | 2.22 | 2.22 |
288.33 | 1.21 | 1.21 |
402.41 | 4.40 | 4.40 |
486.45 | 3.30 | 3.30 |
427.84 | 4.65 | 4.65 |
527.33 | 3.66 | 3.66 |
480.48 | 4.78 | 4.78 |
466.49 | 3.90 | 3.90 |
433.41 | 4.98 | 4.98 |
412.45 | 3.58 | 3.58 |
561.78 | 4.31 | 4.31 |
289.32 | 1.81 | 1.81 |
319.34 | 1.82 | 1.82 |
323.76 | 2.47 | 2.47 |
246.29 | 1.51 | 1.51 |
371.46 | 3.78 | 3.78 |
466.45 | 4.47 | 4.47 |
413.82 | 4.18 | 4.18 |
483.90 | 3.73 | 3.73 |
330.37 | 2.84 | 2.84 |
447.50 | 3.48 | 3.48 |
305.36 | 2.13 | 2.13 |
296.36 | 2.66 | 2.66 |
305.31 | 1.52 | 1.52 |
470.45 | 3.38 | 3.38 |
536.30 | 4.63 | 4.63 |
363.33 | 3.10 | 3.10 |
448.44 | 2.90 | 2.90 |
299.36 | 2.22 | 2.22 |
324.39 | 0.76 | 0.76 |
259.33 | 2.04 | 2.04 |
390.74 | 2.55 | 2.55 |
481.46 | 3.97 | 3.97 |
472.42 | 2.99 | 2.99 |
355.31 | 0.36 | 0.36 |
289.32 | 1.81 | 1.81 |
448.44 | 2.90 | 2.90 |
395.37 | 3.39 | 3.39 |
500.90 | 5.13 | 5.13 |
305.32 | 1.52 | 1.52 |
330.37 | 2.84 | 2.84 |
428.86 | 3.89 | 3.89 |
286.32 | 1.69 | 1.69 |
495.42 | 4.10 | 4.10 |
401.38 | 4.48 | 4.48 |
507.51 | 5.47 | 5.47 |
378.39 | 4.63 | 4.63 |
448.46 | 2.86 | 2.86 |
289.32 | 1.81 | 1.81 |
399.86 | 4.62 | 4.62 |
383.79 | 4.45 | 4.45 |
410.88 | 5.86 | 5.86 |
408.46 | 1.84 | 1.84 |