Basic Information
ID: ALA5140419
Type: Binding
Description: Inhibition of SARS CoV-2 main protease at 50 uM using DABCYL-KTSAVLQSGFRKM-E(EDANS)-NH2 as substrate preincubated for 30 mins followed by substrate addition and measured after 20 mins relative to control
Organism: Severe acute respiratory syndrome coronavirus 2
Activity Charts
Bioactivity
Activity Types for Assay ALA5140419
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.22 | 5.10 | 5.10 |
| 355.35 | 4.59 | 4.59 |
| 416.39 | 4.15 | 4.15 |
| 291.22 | 1.36 | 1.36 |
| 338.44 | 3.51 | 3.51 |
| 445.34 | 3.37 | 3.37 |
| 445.43 | 3.48 | 3.48 |
| 396.47 | 2.38 | 2.38 |
| 346.46 | 2.34 | 2.34 |
| 400.89 | 3.26 | 3.26 |
| 380.47 | 2.92 | 2.92 |
| 290.39 | 2.01 | 2.01 |
| 366.45 | 2.61 | 2.61 |
| 245.31 | 2.11 | 2.11 |
| 303.34 | 2.07 | 2.07 |
| 314.20 | 3.42 | 3.42 |
| 388.40 | 3.42 | 3.42 |
| 290.30 | 2.02 | 2.02 |
| 290.30 | 2.02 | 2.02 |
| 471.43 | 2.78 | 2.78 |
| 303.34 | 2.07 | 2.07 |
| 471.43 | 2.78 | 2.78 |
| 392.37 | 2.93 | 2.93 |
| 342.27 | 1.58 | 1.58 |
| 274.24 | 1.86 | 1.86 |
| 419.46 | 4.18 | 4.18 |
| 366.40 | 4.18 | 4.18 |
| 334.40 | 3.26 | 3.26 |
| 373.39 | 2.33 | 2.33 |
| 346.30 | 2.11 | 2.11 |
| 409.40 | 6.41 | 6.41 |
| 295.37 | 3.27 | 3.27 |
| 334.26 | 1.21 | 1.21 |
| 384.36 | 1.19 | 1.19 |
| 305.38 | 2.28 | 2.28 |
| 433.41 | 4.98 | 4.98 |
| 421.46 | 4.57 | 4.57 |
| 323.76 | 2.47 | 2.47 |
| 295.37 | 3.27 | 3.27 |
| 323.76 | 2.47 | 2.47 |
| 393.47 | 3.95 | 3.95 |
| 303.34 | 2.12 | 2.12 |
| 323.76 | 2.47 | 2.47 |
| 493.52 | 4.74 | 4.74 |
| 342.42 | 2.56 | 2.56 |
| 314.32 | 1.99 | 1.99 |
| 476.52 | 3.97 | 3.97 |
| 502.45 | 3.00 | 3.00 |
| 410.50 | 3.47 | 3.47 |
| 262.34 | 1.14 | 1.14 |
| 302.29 | 2.72 | 2.72 |
| 500.48 | 3.60 | 3.60 |
| 420.85 | 5.41 | 5.41 |
| 461.35 | 4.26 | 4.26 |
| 470.94 | 3.94 | 3.94 |
| 480.48 | 4.78 | 4.78 |
| 466.45 | 4.47 | 4.47 |
| 496.48 | 4.48 | 4.48 |
| 510.42 | 4.83 | 4.83 |
| 496.48 | 4.48 | 4.48 |
| 296.36 | 2.66 | 2.66 |
| 399.86 | 4.62 | 4.62 |
| 264.29 | 1.65 | 1.65 |
| 500.90 | 5.13 | 5.13 |
| 307.31 | 1.95 | 1.95 |
| 414.42 | 4.57 | 4.57 |
| 299.36 | 2.22 | 2.22 |
| 288.33 | 1.21 | 1.21 |
| 402.41 | 4.40 | 4.40 |
| 486.45 | 3.30 | 3.30 |
| 427.84 | 4.65 | 4.65 |
| 346.30 | 1.08 | 1.08 |
| 485.50 | 4.03 | 4.03 |
| 527.33 | 3.66 | 3.66 |
| 492.34 | 3.22 | 3.22 |
| 480.48 | 4.78 | 4.78 |
| 466.49 | 3.90 | 3.90 |
| 433.41 | 4.98 | 4.98 |
| 412.45 | 3.58 | 3.58 |
| 561.78 | 4.31 | 4.31 |
| 289.32 | 1.81 | 1.81 |
| 319.34 | 1.82 | 1.82 |
| 323.76 | 2.47 | 2.47 |
| 367.43 | 2.01 | 2.01 |
| 246.29 | 1.51 | 1.51 |
| 371.46 | 3.78 | 3.78 |
| 466.45 | 4.47 | 4.47 |
| 413.82 | 4.18 | 4.18 |
| 483.90 | 3.73 | 3.73 |
| 384.44 | 2.75 | 2.75 |
| 330.37 | 2.84 | 2.84 |
| 316.43 | 2.35 | 2.35 |
| 446.33 | 2.77 | 2.77 |
| 447.50 | 3.48 | 3.48 |
| 305.36 | 2.13 | 2.13 |
| 392.34 | 3.25 | 3.25 |
| 296.36 | 2.66 | 2.66 |
| 305.31 | 1.52 | 1.52 |
| 470.45 | 3.38 | 3.38 |
| 536.30 | 4.63 | 4.63 |
| 329.43 | 2.03 | 2.03 |
| 363.33 | 3.10 | 3.10 |
| 448.44 | 2.90 | 2.90 |
| 299.36 | 2.22 | 2.22 |
| 397.37 | 2.67 | 2.67 |
| 324.39 | 0.76 | 0.76 |
| 259.33 | 2.04 | 2.04 |
| 390.74 | 2.55 | 2.55 |
| 317.30 | 2.33 | 2.33 |
| 481.46 | 3.97 | 3.97 |
| 472.42 | 2.99 | 2.99 |
| 355.31 | 0.36 | 0.36 |
| 468.92 | 5.54 | 5.54 |
| 424.49 | 3.10 | 3.10 |
| 347.49 | 1.72 | 1.72 |
| 289.32 | 1.81 | 1.81 |
| 448.44 | 2.90 | 2.90 |
| 395.37 | 3.39 | 3.39 |
| 500.90 | 5.13 | 5.13 |
| 305.32 | 1.52 | 1.52 |
| 330.37 | 2.84 | 2.84 |
| 428.86 | 3.89 | 3.89 |
| 286.32 | 1.69 | 1.69 |
| 410.46 | 2.71 | 2.71 |
| 495.42 | 4.10 | 4.10 |
| 401.38 | 4.48 | 4.48 |
| 507.51 | 5.47 | 5.47 |
| 378.39 | 4.63 | 4.63 |
| 448.46 | 2.86 | 2.86 |
| 298.26 | 2.43 | 2.43 |
| 289.32 | 1.81 | 1.81 |
| 399.86 | 4.62 | 4.62 |
| 440.81 | 4.53 | 4.53 |
| 383.79 | 4.45 | 4.45 |
| 410.88 | 5.86 | 5.86 |
| 380.47 | 2.92 | 2.92 |
| 408.46 | 1.84 | 1.84 |