Inhibition of SARS CoV-2 main protease at 50 uM using DABCYL-KTSAVLQSGFRKM-E(EDANS)-NH2 as substrate preincubated for 30 mins followed by substrate ad...

Basic Information

ID: ALA5140419

Type: Binding

Description: Inhibition of SARS CoV-2 main protease at 50 uM using DABCYL-KTSAVLQSGFRKM-E(EDANS)-NH2 as substrate preincubated for 30 mins followed by substrate addition and measured after 20 mins relative to control

Format: BAO_0000357

Organism: Severe acute respiratory syndrome coronavirus 2

Target:  Replicase polyprotein 1ab(ALA4523582)

Document:  ALA5137045

Inhibition of SARS CoV-2 main protease at 50 uM using DABCYL-KTSAVLQSGFRKM-E(EDANS)-NH2 as substrate preincubated for 30 mins followed by substrate addition and measured after 20 mins relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
419.225.105.10
245.312.112.11
303.342.072.07
314.203.423.42
290.302.022.02
290.302.022.02
471.432.782.78
303.342.072.07
471.432.782.78
392.372.932.93
342.271.581.58
274.241.861.86
419.464.184.18
366.404.184.18
334.403.263.26
373.392.332.33
346.302.112.11
409.406.416.41
295.373.273.27
384.361.191.19
305.382.282.28
433.414.984.98
421.464.574.57
323.762.472.47
295.373.273.27
323.762.472.47
393.473.953.95
303.342.122.12
323.762.472.47
493.524.744.74
314.321.991.99
476.523.973.97
502.453.003.00
302.292.722.72
500.483.603.60
461.354.264.26
480.484.784.78
466.454.474.47
496.484.484.48
510.424.834.83
496.484.484.48
296.362.662.66
399.864.624.62
264.291.651.65
500.905.135.13
307.311.951.95
414.424.574.57
299.362.222.22
288.331.211.21
402.414.404.40
486.453.303.30
427.844.654.65
527.333.663.66
480.484.784.78
466.493.903.90
433.414.984.98
412.453.583.58
561.784.314.31
289.321.811.81
319.341.821.82
323.762.472.47
246.291.511.51
371.463.783.78
466.454.474.47
413.824.184.18
483.903.733.73
330.372.842.84
447.503.483.48
305.362.132.13
296.362.662.66
305.311.521.52
470.453.383.38
536.304.634.63
363.333.103.10
448.442.902.90
299.362.222.22
324.390.760.76
259.332.042.04
390.742.552.55
481.463.973.97
472.422.992.99
355.310.360.36
289.321.811.81
448.442.902.90
395.373.393.39
500.905.135.13
305.321.521.52
330.372.842.84
428.863.893.89
286.321.691.69
495.424.104.10
401.384.484.48
507.515.475.47
378.394.634.63
448.462.862.86
289.321.811.81
399.864.624.62
383.794.454.45
410.885.865.86
408.461.841.84