Basic Information
ID: ALA5141269
Type: Functional
Description: Antitumor activity against patient-derived LUPF104 fragment of human NSCLC cells harbouring osimertinib-resistant EGFR Del19/T790M/C797S triple mutant xenografted in NU/NU mouse assessed as reduction in tumor volume at 75 to 100 mg/kg, po bid administered via oral gavage for 56 days
Organism: Homo sapiens
Cell type: NSCLC
Activity Charts
Bioactivity
Activity Types for Assay ALA5141269
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 556.71 | 4.32 | 4.32 |