Basic Information
ID: ALA5141273
Type: Functional
Description: Antagonist activity at human MC4R expressed in CHO cells assessed as decrease in alpha-MSH induced cAMP level by measuring equilibrium binding constant preincubated for 30 mins followed by alpha-MSH addition measured after 30 mins by HTRF method
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA5141273
Kb
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 532.00 | 4.31 | 4.31 |
| 518.02 | 4.29 | 4.29 |
| 480.52 | 3.98 | 3.98 |
| 463.55 | 1.82 | 1.82 |
| 478.98 | 4.04 | 4.04 |
| 482.98 | 2.77 | 2.77 |
| 462.53 | 3.52 | 3.52 |
| 482.42 | 5.29 | 5.29 |
| 475.59 | 3.94 | 3.94 |
| 514.96 | 4.63 | 4.63 |
| 482.54 | 3.92 | 3.92 |
| 463.55 | 1.82 | 1.82 |
| 482.98 | 2.77 | 2.77 |
| 480.52 | 3.98 | 3.98 |