Basic Information
ID: ALA5141434
Type: Binding
Description: Inhibition of human topoisomerase I assessed as DNA unwinding using DNA pBR322 as substrate at 2 uM incubated for 30 mins by ethidium bromide staining based agarose gel electrophoresis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5141434
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 261.71 | 4.09 | 4.09 |
| 124.14 | 0.88 | 0.88 |
| 366.85 | 5.65 | 5.65 |
| 402.83 | 5.31 | 5.31 |
| 398.87 | 5.19 | 5.19 |
| 394.86 | 5.05 | 5.05 |
| 318.38 | 4.07 | 4.07 |
| 352.82 | 4.72 | 4.72 |
| 401.29 | 5.68 | 5.68 |
| 346.43 | 4.50 | 4.50 |
| 398.87 | 5.48 | 5.48 |
| 346.43 | 4.68 | 4.68 |
| 366.85 | 5.03 | 5.03 |
| 384.84 | 5.17 | 5.17 |
| 367.84 | 4.42 | 4.42 |
| 367.83 | 5.08 | 5.08 |
| 332.40 | 4.11 | 4.11 |
| 366.85 | 5.03 | 5.03 |
| 380.88 | 5.05 | 5.05 |
| 382.85 | 4.73 | 4.73 |
| 368.84 | 5.46 | 5.46 |
| 400.84 | 4.87 | 4.87 |
| 304.35 | 4.39 | 4.39 |
| 366.85 | 5.03 | 5.03 |