Basic Information
ID: ALA5141600
Type: Binding
Description: Inhibition of N-terminal human recombinant PKMYT1 (76 to 362 residues) expressed in Escherichia coli (DE3) RIL preincubated with compound for 15 mins in presence of ATP followed by 1 hr incubation by ADP-glo luminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5141600
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 317.35 | 2.56 | 2.56 |
| 319.32 | 1.96 | 1.96 |
| 333.35 | 2.27 | 2.27 |
| 427.47 | 2.98 | 2.98 |
| 343.35 | 2.13 | 2.13 |
| 344.34 | 1.53 | 1.53 |
| 427.47 | 2.98 | 2.98 |
| 377.40 | 1.89 | 1.89 |
| 413.48 | 4.14 | 4.14 |
| 388.21 | 3.27 | 3.27 |
| 367.36 | 3.50 | 3.50 |
| 332.37 | 2.15 | 2.15 |
| 426.27 | 3.34 | 3.34 |
| 357.38 | 2.44 | 2.44 |
| 347.38 | 2.53 | 2.53 |
| 366.81 | 3.65 | 3.65 |
| 413.48 | 4.14 | 4.14 |
| 332.36 | 3.00 | 3.00 |
| 426.27 | 3.34 | 3.34 |
| 426.27 | 3.34 | 3.34 |
| 372.39 | 2.45 | 2.45 |
| 365.82 | 3.53 | 3.53 |
| 413.48 | 4.14 | 4.14 |
| 367.80 | 2.92 | 2.92 |
| 333.35 | 2.27 | 2.27 |
| 426.27 | 3.34 | 3.34 |
| 427.47 | 2.98 | 2.98 |
| 332.36 | 2.87 | 2.87 |
| 372.39 | 2.45 | 2.45 |
| 343.35 | 2.13 | 2.13 |
| 372.39 | 2.45 | 2.45 |
| 367.80 | 2.92 | 2.92 |
| 347.38 | 2.58 | 2.58 |
| 332.36 | 2.87 | 2.87 |
| 361.41 | 2.92 | 2.92 |
| 361.41 | 2.88 | 2.88 |
| 342.36 | 2.74 | 2.74 |
| 333.35 | 2.27 | 2.27 |