Inhibition of N-terminal human recombinant PKMYT1 (76 to 362 residues) expressed in Escherichia coli (DE3) RIL preincubated with compound for 15 mins ...

Basic Information

ID: ALA5141600

Type: Binding

Description: Inhibition of N-terminal human recombinant PKMYT1 (76 to 362 residues) expressed in Escherichia coli (DE3) RIL preincubated with compound for 15 mins in presence of ATP followed by 1 hr incubation by ADP-glo luminescence assay

Format: BAO_0000019

Organism: Homo sapiens

Target: Tyrosine- and threonine-specific cdc2-inhibitory kinase(ALA3984)

Document: ALA5137074

Inhibition of N-terminal human recombinant PKMYT1 (76 to 362 residues) expressed in Escherichia coli (DE3) RIL preincubated with compound for 15 mins in presence of ATP followed by 1 hr incubation by ADP-glo luminescence assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA5141600

IC50

Total(38)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
317.35	2.56	2.56
319.32	1.96	1.96
333.35	2.27	2.27
427.47	2.98	2.98
343.35	2.13	2.13
344.34	1.53	1.53
427.47	2.98	2.98
377.40	1.89	1.89
413.48	4.14	4.14
388.21	3.27	3.27
367.36	3.50	3.50
332.37	2.15	2.15
426.27	3.34	3.34
357.38	2.44	2.44
347.38	2.53	2.53
366.81	3.65	3.65
413.48	4.14	4.14
332.36	3.00	3.00
426.27	3.34	3.34
426.27	3.34	3.34
372.39	2.45	2.45
365.82	3.53	3.53
413.48	4.14	4.14
367.80	2.92	2.92
333.35	2.27	2.27
426.27	3.34	3.34
427.47	2.98	2.98
332.36	2.87	2.87
372.39	2.45	2.45
343.35	2.13	2.13
372.39	2.45	2.45
367.80	2.92	2.92
347.38	2.58	2.58
332.36	2.87	2.87
361.41	2.92	2.92
361.41	2.88	2.88
342.36	2.74	2.74
333.35	2.27	2.27