Inhibition of N-terminal recombinant PKMYT1 (76 to 362 residues) in CCNE1 amplified human FU-OV-1 cells assessed as phosphorylation of CDK1 at Thr14 i...

Basic Information

ID: ALA5141607

Type: Binding

Description: Inhibition of N-terminal recombinant PKMYT1 (76 to 362 residues) in CCNE1 amplified human FU-OV-1 cells assessed as phosphorylation of CDK1 at Thr14 incubated for 2 hrs by AlphaLisa assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: FU-OV-1

Target: Tyrosine- and threonine-specific cdc2-inhibitory kinase(ALA3984)

Document: ALA5137074

Inhibition of N-terminal recombinant PKMYT1 (76 to 362 residues) in CCNE1 amplified human FU-OV-1 cells assessed as phosphorylation of CDK1 at Thr14 incubated for 2 hrs by AlphaLisa assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA5141607

IC50

Total(36)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
333.35	2.27	2.27
311.35	1.73	1.73
427.47	2.98	2.98
427.47	2.98	2.98
344.80	2.99	2.99
310.36	2.34	2.34
311.35	1.73	1.73
413.48	4.14	4.14
388.21	3.27	3.27
355.40	1.65	1.65
426.27	3.34	3.34
410.38	2.76	2.76
413.48	4.14	4.14
332.36	3.00	3.00
426.27	3.34	3.34
426.27	3.34	3.34
372.39	2.45	2.45
413.48	4.14	4.14
336.40	2.91	2.91
367.80	2.92	2.92
333.35	2.27	2.27
426.27	3.34	3.34
427.47	2.98	2.98
330.78	2.68	2.68
372.39	2.45	2.45
324.38	2.65	2.65
372.39	2.45	2.45
325.37	2.04	2.04
382.42	1.26	1.26
337.38	2.30	2.30
367.80	2.92	2.92
347.38	2.58	2.58
332.36	2.87	2.87
380.43	2.55	2.55
297.32	1.42	1.42