Basic Information
ID: ALA5141607
Type: Binding
Description: Inhibition of N-terminal recombinant PKMYT1 (76 to 362 residues) in CCNE1 amplified human FU-OV-1 cells assessed as phosphorylation of CDK1 at Thr14 incubated for 2 hrs by AlphaLisa assay
Organism: Homo sapiens
Cell type: FU-OV-1
Activity Charts
Bioactivity
Activity Types for Assay ALA5141607
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 333.35 | 2.27 | 2.27 |
| 311.35 | 1.73 | 1.73 |
| 427.47 | 2.98 | 2.98 |
| 427.47 | 2.98 | 2.98 |
| 344.80 | 2.99 | 2.99 |
| 310.36 | 2.34 | 2.34 |
| 311.35 | 1.73 | 1.73 |
| 413.48 | 4.14 | 4.14 |
| 388.21 | 3.27 | 3.27 |
| 355.40 | 1.65 | 1.65 |
| 426.27 | 3.34 | 3.34 |
| 410.38 | 2.76 | 2.76 |
| 413.48 | 4.14 | 4.14 |
| 332.36 | 3.00 | 3.00 |
| 426.27 | 3.34 | 3.34 |
| 426.27 | 3.34 | 3.34 |
| 372.39 | 2.45 | 2.45 |
| 413.48 | 4.14 | 4.14 |
| 336.40 | 2.91 | 2.91 |
| 367.80 | 2.92 | 2.92 |
| 333.35 | 2.27 | 2.27 |
| 426.27 | 3.34 | 3.34 |
| 427.47 | 2.98 | 2.98 |
| 330.78 | 2.68 | 2.68 |
| 372.39 | 2.45 | 2.45 |
| 324.38 | 2.65 | 2.65 |
| 372.39 | 2.45 | 2.45 |
| 325.37 | 2.04 | 2.04 |
| 382.42 | 1.26 | 1.26 |
| 337.38 | 2.30 | 2.30 |
| 367.80 | 2.92 | 2.92 |
| 347.38 | 2.58 | 2.58 |
| 332.36 | 2.87 | 2.87 |
| 380.43 | 2.55 | 2.55 |
| 297.32 | 1.42 | 1.42 |