Assay Report Card

Basic Information

ID: ALA5141674

Type: Binding

Description: Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in HEK293FT cells assessed as induction of NSD2 degradation by measuring maximal efficacy at 0.5 to 10 uM incubated for 48 hrs by Western blot analysis relative to control

Organism: Homo sapiens

Cell type: HEK293FT

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
828.842.872.87