Basic Information
ID: ALA5141676
Type: Binding
Description: Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in HEK293FT cells assessed as induction of NSD2 degradation 5 uM incubated for 48 hrs followed by CRBN E3 ligase ligand, pomalidomide addition at 10 uM for last 6 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: HEK293FT
Activity Charts
Bioactivity
Activity Types for Assay ALA5141676
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 828.84 | 2.87 | 2.87 |