Assay Report Card

Basic Information

ID: ALA5141680

Type: Binding

Description: Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in HEK293FT cells assessed as induction of NSD2 degradation 5 uM incubated for 72 hrs followed by compound washout and measured upto 48 hrs post washout by Western blot analysis

Organism: Homo sapiens

Cell type: HEK293FT

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
828.842.872.87