Assay Report Card

Basic Information

ID: ALA5141682

Type: Binding

Description: Protac activity at CRBN E3 ligase/ NSD2 PWWP1 domain (208 to 369 residues) in human NCI-H929 cells assessed as induction of NSD2 degradation 2.5 uM incubated for 72 hrs by Western blot analysis

Organism: Homo sapiens

Cell type: NCI-H929

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
830.863.113.11
842.873.213.21
828.842.872.87
443.462.862.86