Basic Information
ID: ALA5141694
Type: Binding
Description: Protac activity at CRBN/IKZF3 in HEK293FT cells assessed as induction of IKZF3 degradation at 5 uM pretreated with neddylation inhibitor MLN4924 for 2 hrs followed by compound addition and measured after 6 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: HEK293FT
Activity Charts
Bioactivity
Activity Types for Assay ALA5141694
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 828.84 | 2.87 | 2.87 |