Basic Information
ID: ALA5141695
Type: Binding
Description: Protac activity at CRBN/IKZF1 in human KMS-11 cells assessed as induction of IKZF1 degradation at 5 uM pretreated with proteosome inhibitor MLN9708 for 2 hrs followed by compound addition and measured after 6 hrs by Western blot analysis
Organism: Homo sapiens
Cell type: KMS-11
Activity Charts
Bioactivity
Activity Types for Assay ALA5141695
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 828.84 | 2.87 | 2.87 |