Basic Information
ID: ALA5141806
Type: Binding
Description: Inhibition of N-terminal MBP-tagged full length human TPH1 assessed as reduction in 5-HTP formation incubated for 5 to 10 mins by fluorescence microplate reader analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5141806
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 199.64 | 1.29 | 1.29 |
| 404.46 | 2.50 | 2.50 |
| 546.94 | 4.51 | 4.51 |
| 400.44 | 2.42 | 2.42 |
| 484.56 | 1.69 | 1.69 |
| 395.40 | 1.49 | 1.49 |
| 530.55 | 1.07 | 1.07 |
| 444.50 | 2.82 | 2.82 |
| 458.48 | 2.54 | 2.54 |
| 412.45 | 2.74 | 2.74 |
| 503.54 | 2.40 | 2.40 |
| 461.50 | 2.63 | 2.63 |
| 386.42 | 1.94 | 1.94 |
| 428.45 | 2.44 | 2.44 |
| 497.56 | 2.57 | 2.57 |
| 432.51 | 3.37 | 3.37 |
| 419.47 | 2.08 | 2.08 |
| 430.44 | 2.88 | 2.88 |
| 470.49 | 2.52 | 2.52 |
| 437.46 | 2.61 | 2.61 |
| 448.46 | 2.20 | 2.20 |
| 534.56 | 1.24 | 1.24 |
| 444.45 | 2.15 | 2.15 |
| 418.48 | 2.98 | 2.98 |
| 410.42 | 1.19 | 1.19 |
| 548.59 | 1.63 | 1.63 |
| 489.56 | 2.34 | 2.34 |
| 430.47 | 2.52 | 2.52 |
| 472.51 | 2.11 | 2.11 |
| 456.46 | 2.47 | 2.47 |
| 414.47 | 2.81 | 2.81 |
| 471.52 | 1.78 | 1.78 |
| 473.35 | 3.81 | 3.81 |
| 401.43 | 1.52 | 1.52 |
| 484.52 | 1.75 | 1.75 |
| 394.42 | 2.09 | 2.09 |
| 442.48 | 2.75 | 2.75 |
| 425.50 | 2.26 | 2.26 |