Metabolic stability in human liver microsome assessed as intrinsic clearance pretreated for 5 mins followed by NADPH addition and measured upto 60 min...

Basic Information

ID: ALA5141997

Type: ADME

Description: Metabolic stability in human liver microsome assessed as intrinsic clearance pretreated for 5 mins followed by NADPH addition and measured upto 60 mins by HPLC-MS/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target: ADMET(ALA612558)

Document: ALA5137081

Metabolic stability in human liver microsome assessed as intrinsic clearance pretreated for 5 mins followed by NADPH addition and measured upto 60 mins by HPLC-MS/MS analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA5141997

Total(18)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
534.85	2.72	2.72
504.83	2.71	2.71
504.83	2.71	2.71
521.83	3.45	3.45
487.39	2.80	2.80
528.46	2.68	2.68
467.86	2.91	2.91
504.83	2.71	2.71
518.86	3.02	3.02
548.88	3.03	3.03
518.86	3.02	3.02
534.85	2.72	2.72
504.83	2.71	2.71
539.27	3.36	3.36
483.93	3.63	3.63
534.42	3.30	3.30
502.40	2.50	2.50
552.84	2.86	2.86