Basic Information
ID: ALA5142027
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate measured after 5 mins by LC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: Cytochrome P450 3A4(ALA340)
Document: ALA5137081
Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate measured after 5 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5142027
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 518.86 | 3.02 | 3.02 |
| 548.88 | 3.03 | 3.03 |