Basic Information
ID: ALA5142127
Type: Functional
Description: In vivo inhibition of HDAC in ICR mouse allografted with mouse H22 cells assessed as upregulation of acetyl-histone H3 expression at 20 mg/kg, iv qd administered for 21 days measured after 24 hrs by Western blot analysis
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA5142127
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 360.39 | 2.31 | 2.31 |
| 429.45 | 2.12 | 2.12 |