Basic Information
ID: ALA5142248
Type: Binding
Description: Inhibition of TDO (unknown origin) assessed as reduction in N-formylkynurenine formation using L-tryptophan as substrate incubated for 75 mins by UV absorbance based analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5142248
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 182.23 | 3.02 | 3.02 |
| 168.20 | 2.72 | 2.72 |
| 234.26 | 3.11 | 3.11 |
| 250.33 | 4.44 | 4.44 |
| 250.33 | 4.44 | 4.44 |
| 238.26 | 3.87 | 3.87 |
| 244.30 | 4.38 | 4.38 |
| 323.19 | 5.15 | 5.15 |
| 234.26 | 3.98 | 3.98 |
| 278.74 | 5.04 | 5.04 |
| 269.31 | 4.25 | 4.25 |
| 245.28 | 3.78 | 3.78 |
| 278.74 | 5.04 | 5.04 |
| 235.25 | 2.50 | 2.50 |
| 269.31 | 4.25 | 4.25 |
| 262.29 | 4.52 | 4.52 |
| 312.29 | 5.40 | 5.40 |