Basic Information
ID: ALA5142291
Type: Binding
Description: Inhibition of human recombinant renin (67 to 406 residues) expressed in HEK293 cells using Nma-Lys-His-Pro-Phe-His-Leu-Val-Ile-His-Lys-Dnp as fluorescent quenching substrate incubated for 1 hr by FRET analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5142291
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.48 | 2.16 | 2.16 |
| 444.54 | 1.53 | 1.53 |
| 444.54 | 1.53 | 1.53 |
| 430.51 | 1.22 | 1.22 |
| 429.52 | 1.82 | 1.82 |
| 415.49 | 1.26 | 1.26 |
| 372.47 | 1.55 | 1.55 |
| 372.47 | 1.55 | 1.55 |
| 372.47 | 1.55 | 1.55 |
| 414.51 | 1.87 | 1.87 |
| 430.51 | 1.22 | 1.22 |
| 429.52 | 1.57 | 1.57 |
| 372.47 | 1.55 | 1.55 |
| 372.47 | 1.55 | 1.55 |
| 429.52 | 1.82 | 1.82 |
| 429.52 | 1.57 | 1.57 |