Basic Information
ID: ALA5142337
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes incubated for 10 mins in the presence of NADPH by high performance liquid chromatography-tandem mass spectrometry
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA5142337
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 531.44 | 4.21 | 4.21 |
| 486.63 | 4.38 | 4.38 |
| 486.63 | 4.38 | 4.38 |
| 491.05 | 5.02 | 5.02 |
| 470.64 | 4.67 | 4.67 |
| 491.05 | 5.02 | 5.02 |