Assay Report Card

Basic Information

ID: ALA5142348

Type: ADME

Description: Metabolic stability in human liver microsomes assessed as intrinsic clearance preincubated for 10 mins followed by NADPH addition for 2 hrs and measured upto 60 mins by high performance liquid chromatography-tandem mass spectrometry

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
341.453.243.24
284.360.810.81
296.154.364.36
288.433.883.88
486.634.384.38
472.614.074.07
486.634.384.38
491.055.025.02
470.644.674.67
491.055.025.02