Basic Information
ID: ALA5142410
Type: Functional
Description: Antagonist activity at human Galphai2-fused GPR84 stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of PSB-16671-induced [35S]GTPgammaS binding preincubated for 15 mins followed by PSB-16671 addition and measured after 45 mins by liquid scintillation counting analysis
Organism: Homo sapiens
Cell type: Flp-In-T-REx-293
Subcellular Fraction: Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA5142410
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 406.45 | 4.98 | 4.98 |
| 370.33 | 4.51 | 4.51 |
| 462.56 | 4.50 | 4.50 |
| 328.38 | 3.98 | 3.98 |
| 286.34 | 3.61 | 3.61 |
| 370.33 | 4.51 | 4.51 |
| 362.44 | 5.28 | 5.28 |
| 294.40 | 4.19 | 4.19 |
| 419.49 | 4.64 | 4.64 |
| 434.50 | 5.34 | 5.34 |
| 365.40 | 3.46 | 3.46 |
| 364.41 | 4.07 | 4.07 |
| 419.49 | 4.64 | 4.64 |
| 488.60 | 4.67 | 4.67 |
| 433.52 | 4.91 | 4.91 |
| 419.53 | 5.34 | 5.34 |
| 406.45 | 4.98 | 4.98 |
| 478.51 | 4.85 | 4.85 |
| 490.57 | 4.14 | 4.14 |
| 364.41 | 4.07 | 4.07 |
| 455.54 | 4.19 | 4.19 |
| 450.50 | 3.39 | 3.39 |
| 376.46 | 5.59 | 5.59 |
| 364.41 | 4.07 | 4.07 |
| 380.43 | 5.42 | 5.42 |
| 469.57 | 4.33 | 4.33 |
| 440.48 | 5.43 | 5.43 |
| 461.57 | 5.11 | 5.11 |
| 392.46 | 4.77 | 4.77 |
| 461.57 | 5.11 | 5.11 |
| 422.49 | 5.29 | 5.29 |
| 433.52 | 4.91 | 4.91 |
| 423.48 | 4.69 | 4.69 |
| 406.45 | 4.98 | 4.98 |
| 469.57 | 4.33 | 4.33 |
| 363.42 | 4.44 | 4.44 |
| 419.53 | 5.34 | 5.34 |
| 475.55 | 4.75 | 4.75 |
| 434.50 | 5.34 | 5.34 |
| 363.42 | 4.67 | 4.67 |
| 338.41 | 4.39 | 4.39 |
| 420.48 | 4.03 | 4.03 |
| 365.40 | 3.46 | 3.46 |
| 339.40 | 4.21 | 4.21 |
| 374.49 | 5.40 | 5.40 |
| 476.58 | 4.57 | 4.57 |
| 462.56 | 4.50 | 4.50 |
| 327.39 | 3.83 | 3.83 |
| 431.33 | 6.58 | 6.58 |
| 392.46 | 4.77 | 4.77 |
| 463.54 | 4.65 | 4.65 |
| 286.34 | 3.61 | 3.61 |
| 502.58 | 4.19 | 4.19 |
| 406.45 | 4.98 | 4.98 |
| 420.47 | 5.06 | 5.06 |
| 449.51 | 4.00 | 4.00 |
| 363.42 | 4.67 | 4.67 |
| 364.41 | 4.07 | 4.07 |
| 440.53 | 4.68 | 4.68 |
| 420.48 | 4.03 | 4.03 |
| 420.47 | 5.06 | 5.06 |
| 420.47 | 5.06 | 5.06 |
| 450.50 | 3.39 | 3.39 |
| 365.40 | 3.46 | 3.46 |
| 419.49 | 4.64 | 4.64 |
| 303.41 | 4.94 | 4.94 |
| 421.46 | 4.46 | 4.46 |
| 420.47 | 5.06 | 5.06 |
| 420.48 | 4.03 | 4.03 |
| 419.49 | 4.64 | 4.64 |
| 436.52 | 5.31 | 5.31 |
| 398.42 | 5.56 | 5.56 |
| 440.53 | 4.68 | 4.68 |
| 421.46 | 4.46 | 4.46 |
| 420.48 | 4.03 | 4.03 |
| 365.40 | 3.46 | 3.46 |
| 520.23 | 6.80 | 6.80 |
| 462.51 | 3.49 | 3.49 |
| 455.54 | 4.19 | 4.19 |
| 363.42 | 4.67 | 4.67 |