Basic Information
ID: ALA5142725
Type: ADME
Description: Apparent permeability of compound across apical to basolateral in MDCK-II cells expressing human P-glycoprotein gene at 10 uM measured at 2 hrs by LC-MS/MS analysis
Organism: Canis lupus familiaris
Cell type: MDCK-II
Activity Charts
Bioactivity
Activity Types for Assay ALA5142725
Papp
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 452.46 | 4.53 | 4.53 |
| 384.47 | 3.51 | 3.51 |
| 398.49 | 3.82 | 3.82 |
| 452.46 | 4.25 | 4.25 |
| 464.47 | 4.67 | 4.67 |
| 410.50 | 3.90 | 3.90 |
| 452.46 | 4.53 | 4.53 |
| 478.50 | 4.92 | 4.92 |
| 356.41 | 2.62 | 2.62 |
| 436.46 | 4.86 | 4.86 |
| 452.46 | 4.53 | 4.53 |
| 384.47 | 3.23 | 3.23 |