Basic Information
ID: ALA5143769
Type: Binding
Description: Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin)
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5143769
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 475.36 | 4.43 | 4.43 |
| 398.44 | 4.96 | 4.96 |
| 543.67 | 5.62 | 5.62 |
| 426.50 | 5.74 | 5.74 |
| 398.47 | 3.58 | 3.58 |
| 489.55 | 5.30 | 5.30 |
| 475.55 | 5.88 | 5.88 |
| 487.54 | 5.08 | 5.08 |
| 412.47 | 5.35 | 5.35 |
| 571.71 | 4.79 | 4.79 |
| 508.62 | 5.15 | 5.15 |
| 696.73 | 6.86 | 6.86 |
| 318.35 | 4.73 | 4.73 |
| 494.57 | 5.93 | 5.93 |
| 478.57 | 5.81 | 5.81 |
| 508.60 | 6.27 | 6.27 |
| 474.61 | 4.23 | 4.23 |
| 591.72 | 3.94 | 3.94 |
| 510.64 | 5.20 | 5.20 |
| 573.73 | 3.80 | 3.80 |
| 573.73 | 3.80 | 3.80 |
| 496.62 | 4.96 | 4.96 |
| 694.62 | 5.45 | 5.45 |
| 708.65 | 5.70 | 5.70 |
| 318.35 | 4.73 | 4.73 |
| 624.74 | 4.36 | 4.36 |
| 559.65 | 3.36 | 3.36 |
| 584.72 | 6.05 | 6.05 |
| 617.20 | 5.72 | 5.72 |
| 612.22 | 7.14 | 7.14 |
| 416.49 | 2.98 | 2.98 |
| 317.40 | 3.98 | 3.98 |
| 598.19 | 6.75 | 6.75 |
| 510.64 | 5.35 | 5.35 |
| 618.20 | 6.22 | 6.22 |
| 522.65 | 5.49 | 5.49 |