Basic Information
ID: ALA5144238
Type: Binding
Description: Inhibition of recombinant human SENP1 catalytic domain at 2 uM using RanGAP1 as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by Western blot analysis relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: Sentrin-specific protease 1(ALA1909484)
Document: ALA5143517
Inhibition of recombinant human SENP1 catalytic domain at 2 uM using RanGAP1 as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by Western blot analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5144238
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.71 | 7.09 | 7.09 |
| 470.74 | 7.18 | 7.18 |
| 498.75 | 7.66 | 7.66 |
| 569.83 | 6.86 | 6.86 |
| 555.80 | 6.78 | 6.78 |
| 500.76 | 6.54 | 6.54 |
| 570.86 | 7.89 | 7.89 |
| 563.66 | 7.94 | 7.94 |
| 514.75 | 6.63 | 6.63 |
| 568.89 | 6.45 | 6.45 |
| 528.77 | 6.72 | 6.72 |
| 591.72 | 8.72 | 8.72 |
| 455.73 | 6.49 | 6.49 |
| 512.78 | 7.75 | 7.75 |
| 569.87 | 6.88 | 6.88 |
| 597.93 | 7.66 | 7.66 |
| 609.89 | 7.74 | 7.74 |
| 559.88 | 8.88 | 8.88 |
| 571.84 | 6.00 | 6.00 |
| 540.83 | 6.21 | 6.21 |
| 540.83 | 6.26 | 6.26 |
| 586.86 | 4.59 | 4.59 |
| 596.94 | 7.23 | 7.23 |
| 582.87 | 5.98 | 5.98 |
| 604.71 | 8.09 | 8.09 |
| 568.84 | 6.44 | 6.44 |
| 556.83 | 5.23 | 5.23 |
| 553.83 | 7.08 | 7.08 |
| 582.91 | 6.80 | 6.80 |
| 526.81 | 5.87 | 5.87 |
| 712.98 | 9.39 | 9.39 |
| 557.82 | 5.66 | 5.66 |
| 582.87 | 6.83 | 6.83 |
| 611.91 | 7.19 | 7.19 |
| 583.85 | 7.21 | 7.21 |
| 582.87 | 6.78 | 6.78 |
| 497.76 | 7.06 | 7.06 |
| 527.79 | 6.55 | 6.55 |
| 498.75 | 7.36 | 7.36 |
| 583.85 | 7.26 | 7.26 |
| 527.79 | 6.29 | 6.29 |
| 554.82 | 6.18 | 6.18 |
| 570.86 | 5.57 | 5.57 |
| 612.94 | 6.16 | 6.16 |
| 600.89 | 4.93 | 4.93 |
| 527.79 | 6.60 | 6.60 |
| 546.84 | 8.75 | 8.75 |
| 601.92 | 9.45 | 9.45 |
| 567.90 | 8.03 | 8.03 |
| 512.78 | 5.61 | 5.61 |
| 513.76 | 6.21 | 6.21 |
| 562.68 | 7.52 | 7.52 |
| 653.99 | 9.20 | 9.20 |
| 599.90 | 8.07 | 8.07 |