Basic Information
ID: ALA5144253
Type: Functional
Description: Leishmanicidal activity against GFP-expressing axenic amastigote stage of Leishmania infantum MCAN/ES/89/IPZ229/1/89 infected in human THP-1 macrophage cells assessed as reduction in intracellular amastigotes incubated for 48 hrs by propidium iodide staining based flow cytometry
Organism: Leishmania infantum
Strain: MCAN/ES/89/IPZ229/1/89
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA5144253
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.58 | 5.68 | 5.68 |
| 503.67 | 3.97 | 3.97 |
| 469.61 | 4.77 | 4.77 |
| 390.71 | 4.00 | 4.00 |
| 453.95 | 2.88 | 2.88 |