Basic Information
ID: ALA5144473
Type: Binding
Description: Competitive inhibition of human recombinant MGMT expressed in Escherichia coli STAR BL21 pRare cells assessed as cleavage of fluorescent labelled substrate by Bsp 119I at 12.5 uM using O6MeG-bearing substrate (S) incubated for 10 mins in presence of non-substrate CT-DNA followed by substrate addition and measured after 5 mins by coupled enzymatic analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5144473
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 258.71 | 3.63 | 3.63 |
| 241.25 | 1.51 | 1.51 |
| 614.11 | 5.50 | 5.50 |