Basic Information
ID: ALA5144846
Type: Binding
Description: Inhibition of wild-type Transthyretin (unknown origin) expressed in Escherichia coli expression system assessed as acid mediated fibril formation at 7.2 uM measured after 72 hrs by UV-vis spectrophotometry
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA5144846
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 308.12 | 4.50 | 4.50 |
| 366.46 | 3.55 | 3.55 |
| 334.42 | 3.92 | 3.92 |
| 308.39 | 2.94 | 2.94 |
| 338.41 | 2.95 | 2.95 |
| 337.42 | 3.66 | 3.66 |
| 335.40 | 4.05 | 4.05 |
| 336.44 | 3.54 | 3.54 |
| 310.40 | 2.55 | 2.55 |
| 364.45 | 3.93 | 3.93 |