Basic Information
ID: ALA5145098
Type: Binding
Description: Inhibition of SARS-CoV-2 main protease using Mca-AVLQSGFRK(Dnp)K as substrate preincubated with enzyme for 10 mins followed by substrate addition and measured every 30 secs for 10 mins by fluorescence based analysis
Organism: Severe acute respiratory syndrome coronavirus 2
Activity Charts
Bioactivity
Activity Types for Assay ALA5145098
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 169.18 | 1.73 | 1.73 |
| 302.33 | 2.84 | 2.84 |
| 284.34 | 2.70 | 2.70 |
| 227.22 | 1.29 | 1.29 |
| 332.36 | 2.85 | 2.85 |
| 285.28 | 2.11 | 2.11 |
| 294.35 | 2.26 | 2.26 |
| 316.36 | 2.52 | 2.52 |
| 334.33 | 1.61 | 1.61 |
| 299.36 | 2.28 | 2.28 |
| 358.44 | 4.14 | 4.14 |
| 308.38 | 2.65 | 2.65 |
| 336.77 | 3.49 | 3.49 |
| 370.33 | 3.86 | 3.86 |
| 299.36 | 2.28 | 2.28 |
| 332.36 | 2.85 | 2.85 |
| 336.77 | 3.49 | 3.49 |
| 231.28 | 2.70 | 2.70 |
| 352.34 | 3.72 | 3.72 |
| 302.33 | 2.84 | 2.84 |
| 283.32 | 2.54 | 2.54 |
| 314.37 | 2.71 | 2.71 |
| 352.34 | 3.72 | 3.72 |
| 299.36 | 2.28 | 2.28 |
| 318.33 | 2.51 | 2.51 |
| 314.37 | 2.71 | 2.71 |
| 336.77 | 3.49 | 3.49 |
| 302.33 | 2.84 | 2.84 |
| 288.30 | 3.28 | 3.28 |
| 370.33 | 3.86 | 3.86 |
| 299.36 | 2.28 | 2.28 |
| 352.34 | 3.72 | 3.72 |
| 352.34 | 3.72 | 3.72 |
| 287.36 | 3.83 | 3.83 |
| 240.26 | 1.30 | 1.30 |
| 371.22 | 4.15 | 4.15 |
| 314.37 | 2.71 | 2.71 |
| 362.38 | 2.86 | 2.86 |
| 302.33 | 2.84 | 2.84 |
| 332.36 | 2.85 | 2.85 |
| 286.26 | 2.37 | 2.37 |
| 370.33 | 3.86 | 3.86 |
| 330.38 | 2.56 | 2.56 |
| 314.37 | 2.71 | 2.71 |
| 254.29 | 1.34 | 1.34 |