Basic Information
ID: ALA5145638
Type: Binding
Description: Inhibition of TRPC5 channel (unknown origin) expressed in HEK293 cells assessed as inhibition of EA-evoked Ca2+ entry by measuring reduction in intracellular Ca2+ level by Fluo-4 dye based FLIPR assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5145638
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 386.76 | 2.29 | 2.29 |
| 414.82 | 2.75 | 2.75 |
| 456.78 | 2.98 | 2.98 |
| 352.32 | 1.64 | 1.64 |
| 382.34 | 0.94 | 0.94 |
| 424.77 | 2.75 | 2.75 |
| 391.21 | 2.39 | 2.39 |
| 442.76 | 2.89 | 2.89 |
| 386.76 | 2.19 | 2.19 |
| 470.81 | 3.45 | 3.45 |
| 410.78 | 2.42 | 2.42 |
| 442.88 | 3.53 | 3.53 |
| 400.79 | 2.58 | 2.58 |
| 374.75 | 2.19 | 2.19 |
| 456.78 | 3.20 | 3.20 |
| 384.82 | 2.30 | 2.30 |
| 398.78 | 1.85 | 1.85 |
| 368.31 | 0.93 | 0.93 |
| 399.77 | 1.74 | 1.74 |
| 352.32 | 1.64 | 1.64 |
| 459.21 | 3.41 | 3.41 |
| 387.75 | 1.46 | 1.46 |
| 410.78 | 2.42 | 2.42 |
| 424.77 | 2.75 | 2.75 |
| 400.79 | 2.30 | 2.30 |
| 409.20 | 2.53 | 2.53 |
| 442.76 | 2.89 | 2.89 |
| 388.79 | 2.18 | 2.18 |
| 424.77 | 2.75 | 2.75 |
| 396.37 | 0.95 | 0.95 |
| 372.73 | 2.25 | 2.25 |
| 482.82 | 3.77 | 3.77 |
| 400.79 | 2.54 | 2.54 |
| 428.85 | 3.14 | 3.14 |