Basic Information
ID: ALA5145929
Type: Binding
Description: Inhibition of human DGAT1 in serum starved HEK293 cells assessed as inhibition of triglyceride synthesis incubated for 20 mins followed by 13C-addition of 13C-oleic acid pre-complexed with BSA for 120 mins by LC-MS-based mass spectrophotometric analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA5145929
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 455.48 | 6.65 | 6.65 |
| 524.57 | 6.65 | 6.65 |
| 525.56 | 6.05 | 6.05 |
| 526.54 | 4.99 | 4.99 |
| 484.46 | 3.82 | 3.82 |
| 482.49 | 5.48 | 5.48 |